Novel Human-Derived Andes Virus Isolate from an Asymptomatic Contact Reveals a New Haplotype in Chile

Researchers isolated a new human-derived Andes virus strain from an asymptomatic individual identified during prospective follow-up of close contacts of a fatal hantavirus cardiopulmonary syndrome case in Chile. The virus was recovered before antibody development, achieved stable replication in cell culture, and whole-genome sequencing revealed a previously unreported haplotype with culture-adaptive mutations.


Read full article for free (open access):

https://www.sciencedirect.com/science/article/pii/S2666517425001336

Isolation and characterization workflow of the CHI-Hu13724 Andes virus strain from an asymptomatic contact, including cell culture, viral detection, and genome sequencing.



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