Industrialization Drives Convergent Genome Evolution in Human Gut Bacteria Across Global Populations

Researchers analyzed isolate genomes from human gut bacteria collected across industrialized and non-industrialized populations worldwide. Compared with metagenome-assembled genomes, isolates recovered more genes and horizontal gene transfer events. Industrialized populations showed larger proteomes, greater pangenome fluidity, and convergent adaptations affecting stress responses, cell-envelope functions, and metabolism.


Read full article for free (open access):

https://www.sciencedirect.com/science/article/pii/S009286742601264X


Comparative genomic analysis of gut bacteria from industrialized and non-industrialized populations showing increased horizontal gene transfer, proteome expansion, and convergent adaptive evolution in industrialized hosts.


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