How Mucin Enhances Phage Infection and Reduces Biofilm Formation in Yersinia enterocolitica

Mucin plays a key role in shaping interactions between enteropathogenic Yersinia enterocolitica and its mucus-adherent phage fMtkYen801. In vitro, mucin exposure increased phage replication by 100-fold, altered post-infection bacterial growth, and reduced biofilm formation. Resistant variants acquired mutations linked to virulence, quorum sensing, and antibiotic resistance, highlighting implications for phage therapy.


Read full article for free (open access):

https://www.sciencedirect.com/science/article/pii/S2666517426000738



Mucin modulates phage infection dynamics and biofilm formation in enteropathogenic Yersinia enterocolitica

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