Posts

Bacterial tubular networks channel carbohydrates in insect endosymbiosis

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  Highlights • Volume electron microscopy unveils intensive membrane networks in insect symbiotic cells • These tubenets are formed by intracellular bacteria, the insect’s nutritional symbionts • In situ  high spatial resolution chemical analysis shows tubenets’ enrichment in sugar • Bacterial tubenets increase the interface of exchange, maximizing nutrient acquisition

Comparative Analysis of Borrelia’s Defence Mechanisms and Their Impact on Genetic Manipulation of Low-Passage Isolates of Borrelia afzelii and Borrelia garinii

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  Highlights • The  Borrelia  restriction-modification system (RMS) differs by species group. • The RMS affects the transformation efficiency of  Borrelia. • Increase in transformation efficiency observed with an in vitro methylated vector. • Transformation efficiency increased in low-passage  Borrelia  strains. • In vitro methylation can be a facilitating tool for  Borrelia  genetic manipulation.

The antivirulence effect of 5-iodoindole on Vibrio splendidus AJ01 towards Apostichopus japonicus

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  Highlights • Low concentration and high protection without disrupting microbial balance • Dual Protective Mechanism: targeting bacterial virulence and host Immune regulation • Multi-targeted inhibition of bacterial virulence • Elongation factor thermo unstable protein (EF-Tu) is identified as a key target of 5-iodoindole for first time • Superior application prospects for vibrio diseases control in aquaculture

Calyptranema fuscum gen. sp. nov.: a novel cyanobacterial genus within Oculatellaceae based on polyphasic and genomic characterization

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  Highlights • Novel cyanobacterial genus Calyptranema fuscum gen. sp. nov. proposed. • Polyphasic approach combining morphology, phylogeny and genomics used. • ANI, AAI and POCP values confirm taxonomic novelty. • Pangenome analysis reveals genomic diversity within  Oculatellaceae .

Melioidosis in South Asia: The hidden endemicity we can no longer ignore

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  Melioidosis, caused by   Burkholderia pseudomallei , remains one of the most overlooked tropical infections—deadly, yet curable. Despite its discovery more than a century ago, this disease continues to hide behind the masks of tuberculosis, pneumonia, or sepsis, killing silently in regions where it is least recognized. In 2016, modelling studies estimated that South Asia accounts for nearly 44% of the global burden of melioidosis. ( Limmathurotsakul et al., 2016 ) Yet only a handful of countries—India, Sri Lanka, and Bangladesh—routinely diagnose and report human cases. In contrast, neighbouring nations such as Pakistan, Nepal, Bhutan, and Afghanistan have scarcely detected any cases, not because the disease is absent, but because it remains unseen — buried beneath diagnostic inexperience, limited laboratory capacity, and low clinical suspicion. The paradox is striking - while these countries share similar climatic, agricultural, and socioeconomic profiles, the ability to de...

Mercury-driven fungal endophytic community and the role of endophytes in rice grain mercury accumulation

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  Highlights • Mercury (Hg) contamination restructured rice endophytic fungal communities, and higher Hg concentration decreased the richness and diversity of fungal endophytes, and the effect differed with tissues and development stages. • Grains endophytic fungal communities were distinct from roots/stalks/leaves, enriching rare taxa while lacking ubiquitous vegetative endophytes. • Two  Epicoccum nigrum  stains, DHJ7 and FZT214, reduced grains methylmercury by 44.67 % and 48.79 %, respectively. • 62.5 % of tested endophytes improved rice yield under Hg stress, and  Mucor  sp. DHJ19 and  Ceratorhiza  sp. CHJ27 improving yield 72.6–80.5 %.

Revealing unexplored bacterial and fungal variability in interconnected Antarctic brines

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  Highlights • Interconnected Antarctic brines show distinct bacterial and fungal communities • Fine-scale geochemistry and substrate context filter microbial assembly • B2 brine (hypersaline) shows halotolerant bacteria and many unclassified fungi • BCM brine shows permafrost/mineral imprint dominated by Patescibacteria and  Mrakia • BCR brine shows the highest diversity of soil- and glacier-derived microbial taxa