Genomic signatures and host adaptation of H5N1 clade 2.3.4.4b: A call for global surveillance and multi-target antiviral strategies
Highlights • Phylogenetic analysis of genotype B3.13 and D1.1 across the species. • Mutations on the receptor binding sites related to receptor preferring. • Host adaptability differences between B3.13 and D1.1. • Antivirals resistance mutations emergence of genotype B3.13 and D1.1.